Assessment of Improved Aptamers by RNA Rational Design

Stephanie Orraca Albino Author
07/28/2021 Added
36 Plays


Aptamers are single-stranded nucleic acids, DNAs, or RNAs, which recognize a wide variety of molecules. In biotechnology research, their ability to universe specifically and with great affinity to a specific molecule allows them to be used in separation systems. This project It is related to the improvement of these aptamers by putting them in the tetraloop-receptor scaffold (TTR) in chemical mapping experiment and teaches how Spinach and ATP aptamers bind to the desired ligand at different conditions or concentrations so that it has better use over time.

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