NL3 Lab Tour

Kelcey Buck Author

05/15/2020 Added

6 Plays

Description

Virtual tour of the facilities used by Yingying Wang's Neuroimaging for Language, Literacy and Learning (NL3) Lab at the Center for Brain, Biology and Behavior (CB3).

Searchable Transcript

Search:

[00:00:03.370]Hi, my name is YingYing Wang.
[00:00:06.220]I'm currently assistant professor
[00:00:08.800]at University of Nebraska Lincoln,
[00:00:12.520]at the Department of Special Education
[00:00:14.410]and Communication Disorder.
[00:00:16.440]And I'm the director of Neuroimaging
[00:00:19.040]for Language, Literacy and Learning.
[00:00:22.060]So, here we are, here is the MRI simulator room.
[00:00:27.070]And this is one of the system
[00:00:29.380]I use a lot for my one of the project,
[00:00:32.280]is to study children who are learning to read
[00:00:37.240]and how actually the brain changes over time.
[00:00:41.160]And then especially not just in typical children.
[00:00:45.240]And then also in children who are deaf or hard of hearing.
[00:00:48.460]Why we need this simulator is because for younger children,
[00:00:52.030]especially for my interest group,
[00:00:54.630]they are younger than six years old.
[00:00:57.370]So for them to actually adapt to the environment
[00:01:00.140]and to know what the true MRI room will be
[00:01:02.950]and then what the noise is and then what the table is.
[00:01:05.600]And then also we make it a child friendly,
[00:01:07.700]we tell them this is a jungle.
[00:01:09.410]So they will be playing a game in the real MRI room.
[00:01:12.540]So give them a half an hour
[00:01:13.940]before the real session actually increasing
[00:01:16.130]a chance for them to be successful.
[00:01:18.750]My lab is trying to use state of the art,
[00:01:22.880]neuroimaging techniques to understand
[00:01:25.630]biological mechanism of certain behaviors,
[00:01:29.300]of brain plasticity.
[00:01:33.120]Brain plasticity can be due
[00:01:35.830]to experience or maybe some insult
[00:01:39.270]to the brain, traumatic brain injury or stroke
[00:01:41.930]causing the brain to change what happened in the brain.
[00:01:45.390]The neural basis is what I really focus on in our lab.
[00:01:49.250]So currently, we have two main project one we call it BDR,
[00:01:53.920]which stands for Brain Development of Reading.
[00:01:56.590]So we study children.
[00:01:58.250]They are, how their brain changes
[00:02:00.380]over the period that when they learn to read.
[00:02:02.880]Another project, we call BACIC.
[00:02:05.230]So it is Bring Activation of Cochlear Implant Candidates.
[00:02:09.880]So for those individuals,
[00:02:11.500]they are going to get a cochlear implant.
[00:02:13.820]And then we will ask them
[00:02:15.030]to come to our lab to get brain imaging data.
[00:02:18.410]And then also follow them longitudinally.
[00:02:20.810]The goal is we want to understand anything
[00:02:24.500]in the brain, can that help us
[00:02:26.290]to predict their surgical outcomes?
[00:02:29.280]Mostly focus on their speech
[00:02:30.930]perception ability after surgery.
[00:02:33.390]And then, if you don't know about cochlear implant,
[00:02:36.530]it's a device you actually implant
[00:02:38.590]in your inner ear to help those individuals
[00:02:41.660]who has severe to profound hearing loss
[00:02:44.110]to regain the ability to hear.
[00:02:46.170]So this process is not like we get a glasses
[00:02:49.100]and then you have the glasses you can see right away.
[00:02:52.080]Our brains have to adapt to this new device
[00:02:54.850]and to learn, to establish new pathway,
[00:02:58.776]to land a new sensory.
[00:03:00.450]Because the cochlear implant
[00:03:01.860]only gave us a degraded sound signal.
[00:03:04.570]It's not the traditional sound
[00:03:07.160]we hear as a typical hearing person.
[00:03:09.880]So this is the actual EMI system,
[00:03:12.490]and the three Tesla Siemens Skyra.
[00:03:15.700]And this is where actually,
[00:03:18.070]this is the machine my lab use a lot
[00:03:20.020]to collect functional MRI data
[00:03:23.430]and located a Center
[00:03:25.180]for Brain Biology and Behavior, CB3.
[00:03:28.150]So CB3 offers a unique opportunity
[00:03:32.090]for faculties across campus
[00:03:34.510]to collaborate with interdisciplinary projects.
[00:03:38.340]Here you are in the FNIS lab.
[00:03:40.660]So FNIS stands for Functional Near Infrared Spectroscopy.
[00:03:44.670]So if you look at here,
[00:03:46.110]we have those light sensors
[00:03:47.840]and the red is the source and then the blue is the detector.
[00:03:51.180]And then what happens is
[00:03:53.160]when we actually show you a paradigm
[00:03:54.910]to the participants, their brain activity,
[00:03:57.750]we're causing the deoxygenated hemoglobin
[00:04:02.350]actual hemoglobin content changes
[00:04:04.230]and which can be detected by these light sources.
[00:04:07.540]So that's how we can detect the function of the brain.
[00:04:10.800]And then we use this one
[00:04:12.080]to study individuals with cochlear implant
[00:04:14.830]because when someone had a cochlear implant,
[00:04:17.650]they can't go into the MRI scan anymore.
[00:04:20.120]So this device is actually compatible
[00:04:22.870]with the cochlear implant users.
[00:04:25.010]And they're safer for them
[00:04:27.480]to get their imaging, their brain function,
[00:04:30.940]brain imaging scan.

The screen size you are trying to search captions on is too small!

You can always jump over to MediaHub and check it out there.

Comments

0 Comments

NL3 Lab Tour

Description

Searchable Transcript

Comments icon comment

Related Channels

Comments