Computing to Treat Disease
University Communication
Author
04/26/2019
Added
233
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Description
Juan Cui analyzes complex biomedical data with the goal of improving treatment of diseases such as cancer and obesity.
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- [00:00:00.818](upbeat music)
- [00:00:05.010]Our approach we call the data-driven approach
- [00:00:08.550]to studying cancer.
- [00:00:09.480]It's totally different
- [00:00:10.330]from the traditional hypothesis-driven approach, right?
- [00:00:13.210]Which normally focus on
- [00:00:15.310]a very specific functional study of genes or pathways.
- [00:00:20.060]So for us, by analyzing
- [00:00:23.070]multi-levels of molecular profiles simultaneously,
- [00:00:26.720]we believe we can view this complex system
- [00:00:28.970]in a more holistic and system manners.
- [00:00:31.960]So our group is working on the kind of a computational
- [00:00:35.690]system biology and biomedical informatics research.
- [00:00:39.220]So we actually focus on the development
- [00:00:41.720]of all the computational algorithm
- [00:00:43.410]and then mathematic model to analyze biomedical data.
- [00:00:47.070]So that we can address various of important question
- [00:00:50.450]related to complex human disease like obesity and cancer.
- [00:00:54.180]So the idea is that based on the genomics data
- [00:00:57.690]we can collect cancer and normal tissues
- [00:01:00.340]where we make the comparison
- [00:01:01.430]and identify what type of genes
- [00:01:03.030]could be significantly changed
- [00:01:04.670]in cancer population.
- [00:01:06.350]I develop algorithms and mathematical models
- [00:01:09.160]to address biological problems.
- [00:01:11.360]I'm hoping to give insights, the results of my research
- [00:01:16.230]to the medical field to understand
- [00:01:18.424]how to cure the cancer.
- [00:01:20.920]I personally believe in hands-on kind of approach,
- [00:01:25.400]so I prefer to work with my students very closely.
- [00:01:28.660]And there's one thing I always say to them, it's that
- [00:01:31.980]OK, how far you can go in research
- [00:01:34.570]is about your curiosity and then your persistence.
- [00:01:38.020]It's nice to work with her.
- [00:01:40.080]She's expert in bioinformatics and cancer
- [00:01:42.530]and her expertise
- [00:01:45.000]gives me good direction.
- [00:01:46.670]She always give us the good advice.
- [00:01:50.460]She show me like different ways
- [00:01:53.810]computer science and statistic can be used
- [00:01:55.960]in solving problems.
- [00:01:57.360]Our CSE department provide everyone,
- [00:02:00.380]including myself, and then all the students
- [00:02:05.000]excellent theoretical foundations
- [00:02:07.120]and then very solid technical training
- [00:02:09.200]so I think everybody try very hard
- [00:02:11.650]to do whatever needed to help
- [00:02:14.230]each student and us to succeed.
- [00:02:17.128](upbeat music)
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