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[Intro music]

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>> PETA: Today we are here talking to Dr.
David MacMillan, 2015 Hamilton Awardee. Dr.

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MacMillan, thank you for joining us. So you
are basically seen as a hero in our eyes,

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and therefore, if you were a superhero, what
superhero would you be? What superpower would

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you want to have and how would you use that
superpower in chemistry?

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>> DAVID: Yeah, I would say that if it was
going to be doing something in chemistry,

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it would have to be Future Man, whoever Future
Man is. So Future Man would be someone who

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could look into the future a little bit, and
see basically what are the ideas or the concepts

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of things in chemistry, that people are not
thinking about right now. That if you could

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do them, it would be really useful, valuable
- people would be excited about doing it.

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So it's just this idea I've been able to tap
into what's about to happen next. That's the

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part that's pretty cool. So for me, that would
be Future Man, the guy that I would want to

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be, as dorky as that sounds.

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>> PETA: That is awesome. So, there is lot
of discussion about photo redox catalysis

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and how light a huge role plays in your organic
analysis research. What is the inspiring factor

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that made you feel like you should incorporate
light in your research?

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>> DAVID: Well, I think initially, to be completely
honest about it, it was not something that

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we sat down and said alright, we need to get light into our research. As soon

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as we do that, this is going to lead into
this huge field, is going to be incredibly

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exciting. It was a case where we're trying
to solve a completely different problem. And

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we came up with a way of saying, you know
if we use photo redox, which really hadn't

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been used that much, if at all, for organic
chemistry - it had been used a little bit

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in the eighties and a little bit in the nineties
- we said if we use this, we should be able

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to solve this one very specific problem. And
so we did it and it worked. And it was great

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and as soon as we did it, as soon as we started
using light in photo redox, we started to

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realize there were all these other applications
that we could start to use it for, which was

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good. And then two, three, four years later,
we start to see all these other directions

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you can start to think about using it. At
the same time, all these other people did

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too and that was great. So there were all
these different people around the world thinking

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about doing this, which made it really exciting
because it's nice to be involved in a research

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program that you enjoy. There's lots of other
people doing it too makes it really fun, because

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you can get together and talk about it, see
all the directions that they have taken it.

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And so it wasn't really a case of we sat down
and said from day one, yeah this is going

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to be this huge area. It was more a fact that
we study doing it and then realized there

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are all these different directions that we
could take it.

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>> PETA: It's amazing. So other than photo
redox catalysis, what other than that would

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you think is the grand challenge that chemists
are facing today.

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>> DAVID: I mean I would say that of what
we do, the grand challenge is the number one

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challenge is conversion of sunlight into chemical
bonds. This idea of it, can you be able to

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take the energy from the sun and conserve
it some way so that you can utilize it on

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demand for Earth. Right, that's one of the
grand challenges and that's certainly something

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that a lot of people know about. In terms
of grand challenges that no one discusses,

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and the ones I think about, my biggest interest
I think will be a big deal for chemistry going

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forward, is the idea of how you take the basic
units of all these molecules that we have

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right now and use them to inherently do coupling
reactions or bond forming processes, that

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no one is thinking about doing right now.
We are chemistry in that we are fueled to

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set up, is set up pretty well, where we have
these specific functional groups that are

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artificially installed in molecules, so we
can enable molecules to join together. And

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that's good, but it'd be so much better if
you could take all the existing functionality

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and just use that instead. At the moment,
the rules of chemistry are not written such

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that you can do that. So we want to go in
and hopefully change some of the rules and

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allow us to really think about using nato-functionality
to allow molecules to be brought together.

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>> PETA: So I see that have written many papers
- over a hundred, some of them chapters, some

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books - I would love to know how you balance
your time with your personal life and work.

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>> DAVID: I make everybody else do all the
work.

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[laughs]

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>> DAVID: No, basically, how do I balance
my life, I think I'm in pretty privileged

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position. I think I've been lucky to be surrounded
by, throughout my whole career, amazing co-workers

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who drive the research to much great extents
than I ever do, so they do that part. In terms

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of being the boards and consulting and all
those other things, it's been remarkable to

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be involved in all these great people around
the world who would bring you in and sit you

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down and say give us your advice on these
things or your views on that. And remarkably,

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they even listen to it sometimes. To me, it's
not really a balance as much as it's a kind

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of fun, curiosity thing. If you think about
it, for me, I love sports. So I spend a lot

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of time listening to it, thinking about watching
sports. And it's easy and you automatically

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you do it and you think about it because you
enjoy it. And it's the same for chemistry,

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if you feel the same way which I do, and then
you just do it without even thinking about

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it. It's a fun thing to be involved with and
it never feels like work, never feels like

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a hardship. It just feels like something you
are genuinely excited to be doing.

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>> PETA: So, do you have any advice to give
to grad students who, you know, are planning

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on graduating soon?

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>> DAVID: My advice, and it's the same advice
I give to people all the time is kind of simple,

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but it's do what you want to do and don't
do necessarily what your advisor wants you

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to do or your lab mates want you to do or
your mom or your grandma or anyone. Think

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about what is really you're excited about,
what it is that gets you up in the morning

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and sort of follow that and do that. And if
you continue to just go after all those things;

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things will typically work out pretty well.
I sometimes worry that people too often fall

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in a trap of doing what's expected of them
and it's so much more fun to not do that.

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Just go wherever you want to go.

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>> PETA: That is true. Okay, so I have the
big question. You have been here all of yesterday

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and you're here this morning again with us.
How would you describe your tours and your

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talk with students and faculty?

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>> DAVID: So, I came here, I've never been
in Nebraska before, I had no idea what to

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expect. The thing that sort of caught me off
guard was the energy of the place. People

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here are so like you - they're bouncy, they're
jazzy, they want to talk, and they want to

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hear about things. There's a lot of excitement,
people are incredibly friendly, but at the

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same time, really, really, easy to talk to.
But the number one thing for me has been energy.

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There's just been a real strong energy. Everyone
you talk to here are excited about what they're

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doing, they want to tell you what they're
doing and they want to talk about what you're

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doing too. So from that point, it's been,
for me, a really fun trip. A really fun trip.

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>> PETA: So did you think that you were going
to come and see cornfields? And then you saw

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all these huge buildings?

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[Laughs]

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>> DAVID: Exactly. So no, I came here, I had
no idea what I was going to expect. And the

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architecture here is fantastic.

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>> PETA: It's amazing.

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>> DAVID: It's beautiful, right? All these
different buildings and that was wonderful.

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And the other part was meeting the Hamilton
family, which was pretty cool, I thought.

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It's really awesome when you can see people;
that their father and grandfather spent so

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much time caring about this place. And you
can see that keeps going, keeps moving forward,

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that it's part of the fabric of this institution.
And to see these people and interact with

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them, that was pretty cool.

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>> PETA: Well, thank you Dr. MacMillan, we
are very happy to have you join us and be

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a part of our family.

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>> DAVID: Thank you so much, Peta.

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>> PETA: We wish you all the best.

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>> DAVID: Thank you.

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